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Technology

The HPRC generates sequencing data, creates assemblies and pangenomes(see figure below).

Sequencing Data Production

Assembly Generation

The HPRC utilizes NIH’s AnVIL platform to generate assemblies in a open, reproducible way.


Github


Anvil


Dockstore



Pangenome Pipelines

Three different pangenome pipelines are utilzed to create our Year 1 pangenomes.


Minigraph


Minigraph-CACTUS


PGGB