The Human Pangenome Reference Consortium (HPRC) is a project funded by the National Human Genome Research
Instititue to sequence and assemble genomes from individuals from diverse populations in order to better
represent genomic landscape of diverse human populations.
No single genome can represent the diversity in the human population. Using a single reference genome
creates reference biases, adversely affecting variant discovery, gene–disease association studies and
the accuracy of genetic analyses.
The HPRC was started to help migrate common genomic analysis to use a pangenome so diverse populations
are better represented.
